Investigating the function of serum B-HCG levels in the prognosis of hypertensive pregnancy disorders: A prospective observational study

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Original Article

Author Details : Priyanka Rathor*, Anita Inani, Pratibha Vashisth

Volume : 6, Issue : 4, Year : 2023

Article Page : 81-85

https://doi.org/10.18231/j.sajhp.2023.019

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Abstract

Background: Pregnancy-related hypertensive diseases are a serious hazard to world health. Identifying predictive markers is crucial for timely intervention. Serum β-HCG, known for its diverse role in pregnancy, is explored due to its potential involvement in vascular remodeling and angiogenesis.

Materials and Methods: The prospective observational study involves 200 pregnant women, monitored from early gestation to delivery. Serum β-HCG levels are evaluated at different time points. Data collection includes clinical assessments, obstetric evaluations, and blood sample analysis. Statistical analysis is conducted using MedCalc software.

Results: Among 200 cases, elevated serum β-HCG levels (≥2 MoM) show a higher prevalence of hypertensive disorders (HDOP) compared to lower levels (<2 MoM). Maternal and fetal outcomes are explored, revealing adverse outcomes associated with elevated β-HCG levels. Age, religion, and parity distributions are analyzed for their correlation with HDOP.

Conclusion: The study establishes a strong correlation between the onset of HDOP and increased β-HCG levels. There is no discernible relationship between age and HDOP, while religious variations and parity suggest potential relationships. The study also highlights a significant link between proteinuria and HDOP. For a thorough understanding, more studies with bigger sample numbers and controlled designs are advised.

How to cite : Rathor P, Inani A, Vashisth P, Investigating the function of serum B-HCG levels in the prognosis of hypertensive pregnancy disorders: A prospective observational study. South Asian J Health Prof 2023;6(4):81-85

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