This case study presents a detailed homeopathic management of a 40-year-old male suffering from chronic maxillary sinusitis with a deviated nasal septum (DNS). The patient exhibited recurring upper respiratory tract infections, severe anxiety regarding health, and multiple physical and psychological symptoms. After an extensive case analysis and repertorization, individualized homeopathic treatment led to significant improvement in his condition, including reduced frequency and intensity of infections, improved general health, and emotional stability.